Thanks, @angus. I also noticed the order swaps when merging and that did help me test to ensure the hardware was working. The device is a Qwiic LCD module. I’ll look into the Adafruit CircuitPython software and see if I can’t tie into that in some way.
@librecomputer I’d argue disabling the HDMI adapter is acceptable in my case since this setup will never utilize the HDMI adapter. Maybe not the best solution specific to the I2C bus problem, but it would be acceptable for me.