My LePotato started being unresponsive after a while and only the red LED light was turned on. Blue and Green LED lights were off.
In my case I installed Debian 12 with Gnome: debian-12-gnome-arm64+aml-s905x-cc.img.xz.
I disabled the suspend mode on Gnome GUI, but the issue persisted.
Solved it by uncommenting and adding false on /etc/systemd/sleep.conf suspend and hibernation values:
# This file is part of systemd.
#
# systemd is free software; you can redistribute it and/or modify it under the
# terms of the GNU Lesser General Public License as published by the Free
# Software Foundation; either version 2.1 of the License, or (at your option)
# any later version.
#
# Entries in this file show the compile time defaults. Local configuration
# should be created by either modifying this file, or by creating "drop-ins" in
# the sleep.conf.d/ subdirectory. The latter is generally recommended.
# Defaults can be restored by simply deleting this file and all drop-ins.
#
# See systemd-sleep.conf(5) for details.
[Sleep]
AllowSuspend=false
AllowHibernation=false
AllowSuspendThenHibernate=false
AllowHybridSleep=false
SuspendMode=false
#SuspendState=mem standby freeze
#HibernateMode=platform shutdown
#HibernateState=disk
#HybridSleepMode=suspend platform shutdown
#HybridSleepState=disk
#HibernateDelaySec=
#SuspendEstimationSec=60min
After that, you can reboot for the changes to sur effect.